D u e to its low antigenic mass, each virus particle b i n d s v e r y f e w a n t i b o d y m o l e c u l e s so t h a t t h e d i r e c t d e t e c t i o n o f l o w c o n c e n t r a t i o n s o f viruses is d i f f i c u l t o r i m p o s s i b l e. M u c h less a t t e n t i o n has b e e n given t o t h e d e t e c t i o n o f t h e l o w c o n c e n t r a t i o n s o f viruses w h i c h a r e p r e s e n t d u r i n g early stages o f i n f e c t i o n, in air o r w a t e r samples, or in t h e b l o o d used f o r t r a n s f u s i o n p u r p o s e s. Successful diagnosis d e p e n d s u p o n t h e p r e s e n c e o f c o m p a r a t i v e l y large a m o u n t s o f virus-specific antigens at a relatively late stage o f virus i n f e c t i o n. INTRODUCTION L a b o r a t o r y m e t h o d s f o r t h e r a p i d diagnosis o f virus i n f e c t i o n s f r e q u e n t l y involve t h e e x a m i n a t i o n o f b i o p s y s p e c i m e n s f o r t h e p r e s e n c e o f virusspecific antigens in i n f e c t e d cells b y t h e use o f radio- or f l u o r e s c e n t - l a b e l l e d a n t i b o d i e s or, m o r e r e c e n t l y, e n z y m e - l i n k e d a n t i b o d i e s. Direct assays using ELA were more rapid and easier to perform than the other assay methods. Direct and indirect assays using enzyme-linked antibodies (ELA) were slightly less sensitive than the direct RLA and PAP methods but were more sensitive than the indirect RLA or fluorescent antibody (FLA) methods. Direct assays with radio-labelled antibody (RLA) and indirect assays using peroxidase-antiperoxidase complexes (PAP) were equally sensitive. The importance of several reaction variables has been investigated and the sensitivity of the methods compared for different periods of virus replication. (Received 26 July 1978, accepted 8 August 1978)ДЄ number of labelled antibody methods have been applied to the detection of Semliki Forest virus antigens after replication of the virus in monolayers of host cells in multi-well polystyrene plates. CROOKS Microbiological Research Establishment, Porton Down, Salisbury, Wilts. В© Elsevier/North-Holland Biomedical PressДЄ COMPARISON OF LABELLED ANTIBODY METHODS FOR THE DETECTION OF VIRUS ANTIGENS IN CELL MONOLAYERS Vickers M15 Jumelles Microscope + 3 Objectifs 100/1.3 Huile,40x 0.70 PH2,( Plan Vickers Instruments M41 Photoplan Microscope Vickers Photoplan Microscope Body and head. VICKERS INSTRUMENTS MICROSCOPE LAB INDUSTRIAL VICKERS INSTRUMENTS MICROCAM FIBRE LAUNCH ILLUMINATOR MICROSCOPE Vickers Instruments Binocular Microscope M14/2 Patent no 877813 in wooden case Vickers Strumenti Binocolo Microscopio + 4 Obiettivi 100/1.3 Olio, 40/0.70 Lab Vickers Model M15c Phase-Contrast Binocular Microscope + 6 Objectives Lab Vickers Stereo Microscope With Adjustment Arm Vickers Instruments Stereo Microscope M14/2 NO LENS No Objective Vickers Instruments Microscope Objective lenses ,set of 4 ( 7x, 30x, 70x, 140x) Vickers Photoplan Microscope w / 1 Objective, 1 Lamp Vintage Black Monocular Vickers Microscope with 4 Objectives Cooke & Baker Check out our selection and we're sure you'll agree! If you need affordable high-performance microscopes and related instruments for your lab, business or school Microscope Showroom has exactly what you're looking for no matter what industry you're in. We have teamed up with ebay so that we can provide the most extensive and diverse selection of competitively priced new and used precision Vickers microscopes and microscope accessories that any site offers. From industrial microscopes including digital microscopes, video inspection systems, stereoscopes, and inspection microscopes to scientific microscopes such as electron microscopes and confocal light microscopes, Microscope Showroom is the only name you need to remember for great deals on microscopes from the industry's top equipment providers like Vickers. Microscope Showroom specializes in just one thing - precision medical, laboratory, industrial and educational microscopes. Let Vickers put their vast expertise to work for you with an affordably priced microscope from our vast selection of Vickers instruments. All types of operations and usages for microscopic instrumentation including industrial, scientific, biological, medical, electronic, metallurgical and educational applications can be effectively handled with Vickers's innovative and well-engineered microscopes and accessories. Vickers is one of the industry's top providers of full-featured and ultra-precision industrial, medical and scientific microscopes.

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